Text table 2
Mortality reduction associated with adjuvant treatment, by receptor status, age range, and breast cancer stage
| Receptor status | Age | Mortality reduction, % (treatment type) | |
|---|---|---|---|
| Ductal carcinoma in situ | Invasive cancer, including distant | ||
| ER + | Younger than 50 50 or older |
32 (tamoxifen) 32 (tamoxifen) |
58 (chemotherapy and tamoxifen) 53 (chemotherapy and aromatase inhibitor) |
| ER - | Younger than 50 50 or older |
0 (no adjuvant) 0 (no adjuvant) |
38 (chemotherapy) 38 (chemotherapy) |
| HER2+ | All ages | 0 (no adjuvant) | 33 (herceptin) |
|
ER+/ER- = estrogen receptor positive/estrogen receptor negative HER2 = human epidermal growth factor receptor 2 Source: Early Breast Cancer Trialists’ Collaborative Group (EBCTCG).Note 11 |
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