Table 3-2
Changes in five-year observed survival proportions over time by diagnostic group and selected subgroup, ages 0 to 14 at diagnosis, Canada excluding Quebec, 1992-to-1996 period to 2013-to-2017 period — Part 2
Diagnostic group / subgroup | Time period | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Change (% points) |
1992-to-1996 to 2013-to-2017 |
Change (% points) |
1992-to-1996 to 2003-to-2007 |
Change (% points) |
2003-to-2007 to 2013-to-2017 |
|||||||
95% CI | P-value | 95% CI | P-value | 95% CI | P-value | |||||||
from | to | from | to | from | to | |||||||
All groups | 7.5 | 5.6 | 9.3 | < 0.001 | 6.2 | 4.3 | 8.1 | < 0.001 | 1.3 | -0.4 | 3.0 | 0.134 |
I. Leukemias, myeloproliferative diseases, and myelodysplastic diseases | 10.3 | 7.3 | 13.3 | < 0.001 | 9.4 | 6.2 | 12.5 | < 0.001 | 0.9 | -1.7 | 3.6 | 0.484 |
a. Lymphoid leukemias | 8.0 | 5.1 | 10.8 | < 0.001 | 6.1 | 3.0 | 9.1 | < 0.001 | 1.9 | -0.5 | 4.3 | 0.126 |
b. Acute myeloid leukemias | 16.6 | 6.4 | 26.8 | 0.001 | 23.5 | 13.2 | 33.9 | < 0.001 | -7.0 | -16.9 | 2.9 | 0.167 |
c. Chronic myeloproliferative diseases | 35.4 | 15.7 | 55.0 | < 0.001 | 32.5 | 9.9 | 55.1 | 0.005 | 2.9 | -12.5 | 18.2 | 0.714 |
II. Lymphomas and reticuloendothelial neoplasms | 7.5 | 2.9 | 12.1 | 0.001 | 7.1 | 2.3 | 12.0 | 0.004 | 0.4 | -3.3 | 4.1 | 0.839 |
a. Hodgkin lymphomas | 9.4 | 4.1 | 14.7 | < 0.001 | 9.5 | 4.3 | 14.8 | 0.000 | -0.1 | -2.1 | 1.9 | 0.934 |
b. Non-Hodgkin lymphomas (except Burkitt lymphoma) | 7.0 | -2.8 | 16.8 | 0.159 | 12.8 | 2.8 | 22.9 | 0.012 | -5.8 | -13.6 | 2.0 | 0.143 |
c. Burkitt lymphoma | 1.6 | -7.9 | 11.1 | 0.746 | -3.8 | -15.2 | 7.6 | 0.515 | 5.4 | -5.2 | 16.0 | 0.321 |
d. Miscellaneous lymphoreticular neoplasms | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | 20.6 | 2.0 | 39.3 | 0.030 |
III. CNS and miscellaneous intracranial and intraspinal neoplasms | 5.2 | 0.4 | 10.1 | 0.034 | 4.4 | -0.5 | 9.4 | 0.079 | 0.8 | -4.1 | 5.6 | 0.750 |
a. Ependymomas and choroid plexus tumour | 32.1 | 16.3 | 47.8 | < 0.001 | 19.8 | 2.4 | 37.3 | 0.026 | 12.3 | -2.9 | 27.4 | 0.112 |
b. Astrocytomas | -0.8 | -6.6 | 5.0 | 0.784 | 0.4 | -5.5 | 6.3 | 0.897 | -1.2 | -7.3 | 4.9 | 0.700 |
c. Intracranial and intraspinal embryonal tumours | 16.6 | 6.5 | 26.7 | 0.001 | 4.1 | -6.8 | 15.0 | 0.457 | 12.5 | 1.8 | 23.1 | 0.021 |
d. Other gliomas | -2.8 | -16.7 | 11.1 | 0.694 | 15.3 | 0.6 | 29.9 | 0.041 | -18.1 | -31.8 | -4.3 | 0.010 |
IV. Neuroblastoma and other peripheral nervous cell tumours | 18.8 | 10.9 | 26.7 | < 0.001 | 13.5 | 5.1 | 21.9 | 0.002 | 5.3 | -1.7 | 12.3 | 0.137 |
a. Neuroblastoma and ganglioneuroblastoma | 19.4 | 11.5 | 27.3 | < 0.001 | 13.8 | 5.3 | 22.3 | 0.001 | 5.6 | -1.4 | 12.7 | 0.119 |
V. Retinoblastoma | -4.8 | -10.8 | 1.2 | 0.116 | -5.1 | -11.3 | 1.1 | 0.110 | 0.3 | -7.8 | 8.4 | 0.942 |
VI. Renal tumours | 8.7 | 3.1 | 14.2 | 0.002 | -1.9 | -8.9 | 5.2 | 0.603 | 10.6 | 4.4 | 16.7 | 0.001 |
a. Nephroblastoma and other nonepithelial renal tumours | 9.5 | 3.8 | 15.1 | 0.001 | -0.7 | -7.9 | 6.6 | 0.856 | 10.1 | 4.0 | 16.3 | 0.001 |
VII. Hepatic tumours | 2.0 | -15.5 | 19.4 | 0.826 | 0.5 | -17.0 | 17.9 | 0.957 | 1.5 | -16.1 | 19.1 | 0.870 |
VIII. Malignant bone tumours | -0.9 | -11.1 | 9.2 | 0.858 | -4.9 | -15.3 | 5.4 | 0.352 | 4.0 | -6.2 | 14.2 | 0.445 |
a. Osteosarcomas | -1.3 | -16.0 | 13.5 | 0.865 | 3.7 | -10.8 | 18.3 | 0.616 | -5.0 | -19.7 | 9.7 | 0.503 |
c. Ewing tumour and related sarcomas of bone | 2.6 | -13.4 | 18.5 | 0.753 | -12.1 | -28.9 | 4.6 | 0.156 | 14.7 | -0.7 | 30.1 | 0.061 |
IX. Soft tissue and other extraosseous sarcomas | 0.0 | -8.3 | 8.2 | 0.991 | -2.1 | -10.8 | 6.6 | 0.638 | 2.1 | -6.6 | 10.7 | 0.641 |
a. Rhabdomyosarcomas | 1.6 | -10.1 | 13.4 | 0.785 | -4.3 | -17.0 | 8.4 | 0.508 | 5.9 | -7.0 | 18.8 | 0.367 |
d. Other specified soft tissue sarcomas | -8.2 | -22.9 | 6.6 | 0.277 | -2.2 | -17.1 | 12.8 | 0.774 | -6.0 | -20.5 | 8.5 | 0.418 |
X. Germ cell tumours, trophoblastic tumours, and neoplasms of gonads | 4.9 | -3.2 | 13.0 | 0.238 | 4.8 | -3.6 | 13.1 | 0.262 | 0.1 | -7.3 | 7.5 | 0.975 |
b. Malignant extracranial and extragonadal germ cell tumours | 3.3 | -13.0 | 19.6 | 0.690 | 8.5 | -6.6 | 23.5 | 0.270 | -5.1 | -17.4 | 7.1 | 0.410 |
c. Malignant gonadal germ cell tumours | 3.2 | -4.8 | 11.2 | 0.431 | 1.3 | -7.5 | 10.0 | 0.775 | 1.9 | -5.8 | 9.7 | 0.626 |
XI. Other malignant epithelial neoplasms and malignant melanomas | 5.9 | -1.7 | 13.6 | 0.129 | 7.9 | 0.1 | 15.7 | 0.047 | -2.0 | -7.9 | 4.0 | 0.517 |
b. Thyroid carcinomas | 2.6 | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | 2.6 | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | 0.0 | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period |
f. Other and unspecified carcinomas | 11.9 | -3.0 | 26.8 | 0.117 | 6.2 | -11.7 | 24.1 | 0.500 | 5.8 | -9.1 | 20.6 | 0.447 |
XII. Other and unspecified malignant neoplasms | -10.9 | -31.2 | 9.5 | 0.296 | 2.1 | -10.2 | 14.3 | 0.743 | -12.9 | -31.9 | 6.1 | 0.182 |
.. not available for a specific reference period E Use with caution F too unreliable to be published Notes: OSP = observed survival proportion; CI = confidence interval; CNS = central nervous system. OSPs for all groups combined were calculated as a weighted average of sex- and diagnostic-group-specific estimates. Quebec is excluded because cases diagnosed in Quebec from 2011 onward had not been submitted to the Canadian Cancer Registry. All estimates are based on invasive behaviour cases only. OSPs for the 2013-to-2017 period were predicted using the period method. The use of caution is suggested in the interpretation of estimates associated with an unrounded standard error > 0.05 and ≤ 0.10.; if > 0.10, estimates were considered too unreliable to be published. Differences in survival over the full period may not equal the sum of differences for the subperiods because of rounding. Source: Statistics Canada, Canadian Cancer Registry death linked file (1992 to 2017). |
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