Table 1
Cohort characteristics, opioid-naïve children (aged 1 to 24 years) of opioid-naïve mothers who underwent surgery in Ontario, Canada, July 2013 to March 2017
| Characteristic | Total/overall (n=283,550) |
Mother filled postoperative opioid prescription (n=171,139) |
Mother did not fill postoperative opioid prescription (n=112,411) |
P-valueTable 1 Note ‡ | |||
|---|---|---|---|---|---|---|---|
| mean | standard deviation | mean | standard deviation | mean | standard deviation | p-valueTable 1 Note ‡ | |
| Age, child, years | 10.6 | 6.6 | 11.0 | 6.8 | 10.0 | 6.8 | <0.001 |
| Age, mother, years | 40.2 | 8.3 | 40.7 | 8.2 | 39.4 | 8.4 | <0.001 |
| number | percent | number | percent | number | percent | p-valueTable 1 Note ‡ | |
| Sex, male | 146,951 | 51.8 | 88,505 | 51.7 | 58,446 | 52.0 | 0.15 |
| Residence | |||||||
| Rural | 38,571 | 13.6 | 22,480 | 13.1 | 16,091 | 14.3 | <0.001 |
| Non-rural | 244,979 | 86.4 | 148,659 | 86.9 | 96,320 | 85.7 | N/A |
| Neighbourhood income quintile | |||||||
| First (lowest) | 49,852 | 17.6 | 28,307 | 16.5 | 21,545 | 19.2 | <0.001 |
| Second | 51,700 | 18.2 | 30,502 | 17.8 | 21,198 | 18.9 | N/A |
| Third | 57,094 | 20.1 | 34,490 | 20.2 | 22,604 | 20.1 | N/A |
| Fourth | 64,581 | 22.8 | 39,998 | 23.4 | 24,583 | 21.9 | N/A |
| Fifth (highest) | 57,930 | 20.4 | 36,559 | 21.4 | 21,371 | 19.0 | N/A |
| Missing | 2,393 | 0.8 | 1,283 | 0.7 | 1,110 | 1.0 | N/A |
Sources: 1. Inpatient admissions (Discharge Abstract Database), 2. Same-day surgical procedures (Same Day Surgery Database), 3. Opioid prescriptions (Narcotics Monitoring System), 4. Emergency department presentations (National Ambulatory Care Reporting System), 5. Deaths (Office of the Registrar General – Deaths) and individual-level demographic information (Registered Persons Database), 6. Mother–baby linked database (ICES-derived MOMBABY database). |
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