Table 2
Sex-specific trends in thyroid cancer age-standardized incidence rates (ASIRs), by histologic type and province, Canada excluding Quebec, 1992 to 2016
| Trend analysis | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Female | Male | |||||||||
| Period | Annual percent change in ASIR | 95% confidence interval | p-value | Period | Annual percent change in ASIR | 95% confidence interval | p-value | |||
| from | to | from | to | |||||||
| All | 1992 to 1998 | 2.5 | -0.4 | 5.5 | 0.088 | 1992 to 2012 | 6.5 | 5.9 | 7.2 | <0.001 |
| 1998 to 2003 | 11.4 | 6.9 | 16.1 | <0.001 | 2012 to 2016 | 1.2 | -3.2 | 5.8 | 0.575 | |
| 2003 to 2012 | 6.1 | 5.0 | 7.2 | <0.001 | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | |
| 2012 to 2016 | -3.0 | -5.5 | -0.4 | 0.025 | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | |
| Histology | ||||||||||
| Papillary | 1992 to 1997 | 1.8 | -2.4 | 6.1 | 0.379 | 1992 to 2012 | 8.1 | 7.4 | 8.9 | <0.001 |
| 1997 to 2002 | 12.9 | 7.7 | 18.4 | <0.001 | 2012 to 2016 | 1.0 | -3.6 | 5.9 | 0.649 | |
| 2002 to 2012 | 7.7 | 6.7 | 8.7 | <0.001 | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | |
| 2012 to 2016 | -3.7 | -6.1 | -1.2 | 0.007 | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | |
| Non-papillary | 1992 to 2016 | 0.2 | -0.4 | 0.7 | 0.575 | 1992 to 2016 | 1.1 | 0.4 | 1.9 | 0.005 |
| Follicular | 1992 to 2016 | -0.2 | -0.9 | 0.5 | 0.520 | 1992 to 2016 | 0.1 | -0.9 | 1.1 | 0.830 |
| Medullary | 1992 to 2016 | 1.9 | 0.6 | 3.1 | 0.004 | 1992 to 2016 | 3.0 | 2.1 | 4.0 | <0.001 |
| Anaplastic | 1992 to 2016 | -1.7 | -2.9 | -0.5 | 0.007 | 1992 to 2016 | 1.3 | -0.3 | 3.0 | 0.101 |
| Other specified | 1992 to 2016 | 2.3 | 0.7 | 3.9 | 0.006 | 1992 to 2016 | 1.5 | -0.9 | 4.0 | 0.221 |
| Unspecified | 1992 to 2005 | 5.7 | 0.8 | 10.7 | 0.023 | 1992 to 2004 | 2.3 | -2.2 | 7.0 | 0.307 |
| 2005 to 2016 | -17.2 | -23.1 | -10.9 | <0.001 | 2004 to 2016 | -8.3 | -12.2 | -4.2 | <0.001 | |
| Province | ||||||||||
| British Columbia | 1992 to 2016 | 3.5 | 3.0 | 4.1 | <0.001 | 1992 to 2016 | 3.5 | 2.8 | 4.1 | <0.001 |
| Alberta | 1992 to 2005 | 7.1 | 5.2 | 9.1 | <0.001 | 1992 to 2016 | 3.7 | 2.9 | 4.6 | <0.001 |
| 2005 to 2016 | 1.3 | -0.3 | 2.8 | 0.100 | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | |
| Saskatchewan | 1992 to 2016 | 3.6 | 2.6 | 4.6 | <0.001 | 1992 to 2016 | 3.8 | 2.7 | 4.9 | <0.001 |
| Manitoba | 1992 to 2016 | 4.6 | 3.5 | 5.7 | <0.001 | 1992 to 2016 | 5.1 | 3.9 | 6.4 | <0.001 |
| Ontario | 1992 to 1997 | 1.2 | -3.5 | 6.1 | 0.612 | 1992 to 2016 | 6.7 | 6.0 | 7.4 | <0.001 |
| 1997 to 2002 | 13.9 | 7.9 | 20.2 | <0.001 | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | |
| 2002 to 2012 | 6.8 | 5.7 | 7.9 | <0.001 | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | |
| 2012 to 2016 | -3.1 | -5.9 | -0.1 | 0.041 | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | |
| New Brunswick | 1992 to 1998 | -4.3 | -12.5 | 4.7 | 0.311 | 1992 to 2008 | 10.7 | 6.9 | 14.5 | <0.001 |
| 1998 to 2005 | 18.3 | 10.2 | 27.0 | <0.001 | 2008 to 2016 | 0.2 | -5.7 | 6.5 | 0.937 | |
| 2005 to 2011 | 4.4 | -1.9 | 11.2 | 0.162 | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | |
| 2011 to 2016 | -10.2 | -16.4 | -3.7 | 0.005 | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | |
| Nova Scotia | 1992 to 2001 | 0.6 | -5.8 | 7.4 | 0.859 | 1992 to 2006 | 11.1 | 7.2 | 15.1 | <0.001 |
| 2001 to 2006 | 18.9 | -0.5 | 41.9 | 0.056 | 2006 to 2016 | 3.2 | -0.4 | 7.0 | 0.076 | |
| 2006 to 2016 | 1.4 | -2.0 | 4.8 | 0.402 | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | Note ...: not applicable | |
| Prince Edward Island | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period | Note ..: not available for a specific reference period |
| Newfoundland and Labrador | 1992 to 2016 | 8.4 | 6.7 | 10.1 | <0.001 | 1992 to 2016 | 7.1 | 4.6 | 9.6 | <0.001 |
|
.. not available for a specific reference period ... not applicable Notes: Quebec is excluded because cases diagnosed in Quebec from 2011 onward had not been submitted to the Canadian Cancer Registry. Trends associated with a p-value > 0.05 were considered stable. Otherwise, positive (increasing) or negative (decreasing) annual percent changes were considered as actual changes in the ASIR over time. Trends were not available for Prince Edward Island because there were no cases of thyroid cancer in one or more years during the reference period. Source: Statistics Canada, Canadian Cancer Registry. |
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