Table 5
Selected screening program scenarios, Cancer Risk Management Model-Lung Cancer (CRMM-LC) and Cancer Intervention and Surveillance Modeling Network (CISNET)

Table 5
Selected screening program scenarios, Cancer Risk Management Model-Lung Cancer (CRMM-LC) and Cancer Intervention and Surveillance Modeling Network (CISNET)
Table summary
This table displays the results of Selected screening program scenarios. The information is grouped by Screening frequency (appearing as row headers), Scenario, Percentage ever screened (%) , Screenings per 100,000 , Over-diagnosis (% of screen-detected cases) , Percentage of cases detected at early stage (%), Lung cancer mortality reduction (%), Life-years gained per 100,000 , Number of persons needed to screen (ever) per lung cancer death averted, Age, Pack-years smoked and Years former smoker (appearing as column headers).
Screening frequency Scenario Percentage ever screened (%)Note * Screenings per 100,000 Over-diagnosis (% of screen-detected cases) Percentage of cases detected at early stage (%)Note † Lung cancer mortality reduction (%)Note ‡ Life-years gained per 100,000 Number of persons needed to screen (ever) per lung cancer death averted
Age Pack-years smoked Years former smoker
Start screening End screening CRMM CISNET CRMM CISNET CRMM CISNET CRMM CISNET CRMM CISNET CRMM CISNET CRMM CISNET
Annual 55 80 30 15 16.4 19.3 339,729 286,813 23.4 9.9 42.2 50.5 8.0 14.0 5,539 5,517 42 37
Biennial 60 85 30 20 15.6 17.9 154,694 127,046 17.9 11.5 36.9 47.5 7.5 9.6 4,429 3,451 43 50
Triennial 60 85 40 25 10.6 13.0 71,508 66,333 9.4 13.1 31.4 44.1 5.9 6.0 3,412 2,252 36 58
Note *

incident cases in no-screening scenario were 6,288 per 100,000 persons in CRMM-LC and 5,119 in CISNET

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Note †

percentage of cases detected at early stage in no-screening scenario was 26.9% in CRMM-LC and 37.4% in CISNET (stages I and II)

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Note ‡

average lung cancer deaths in no-screening scenario were 5,203 per 100,000 persons in CRMM-LC and 3,719 in CISNET

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Notes: All counts are cumulative per cohort of 100,000 persons aged 45 followed to age 90 and having perfect adherence to screening. A comparison of the full set of 26 scenarios reported by CISNET is available from the authors.
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